2-FLUORO-5-HYDROXYMETHYLPHENYLBORONIC ACID
97%
- Product Code: 187296
Alias:
2-Fluoro-5-(hydroxymethyl)benzeneboric acid
CAS:
1072952-25-0
| Molecular Weight: | 169.95 g./mol | Molecular Formula: | C₇H₈|BFO₃ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 70-72°C | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
Used in the synthesis of pharmaceutical intermediates, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds found in active drug substances. Serves as a building block in medicinal chemistry for developing fluorinated organic molecules with enhanced metabolic stability and binding affinity. Its boronic acid group enables rapid derivatization, while the fluorine atom acts as a bioisostere and improves pharmacokinetic properties. Commonly applied in research settings for drug discovery in oncology, CNS disorders, and antiviral therapies. Also utilized in the preparation of sensors and functional materials due to its selective reactivity and structural features.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿26.00 |
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| 5g | 10-20 days | ฿820.00 |
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| 25g | 10-20 days | ฿4,020.00 |
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2-FLUORO-5-HYDROXYMETHYLPHENYLBORONIC ACID
Used in the synthesis of pharmaceutical intermediates, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds found in active drug substances. Serves as a building block in medicinal chemistry for developing fluorinated organic molecules with enhanced metabolic stability and binding affinity. Its boronic acid group enables rapid derivatization, while the fluorine atom acts as a bioisostere and improves pharmacokinetic properties. Commonly applied in research settings for drug discovery in oncology, CNS disorders, and antiviral therapies. Also utilized in the preparation of sensors and functional materials due to its selective reactivity and structural features.
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