3-fluoroazetidine hydrochloride
98%
- Product Code: 187389
CAS:
617718-46-4
| Molecular Weight: | 111.55 g./mol | Molecular Formula: | C₃H₆FN·HCl |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD05663715 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its strained azetidine ring enhances binding affinity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship optimization, especially in kinase inhibitors and GPCR-targeted agents. The fluorine atom improves membrane permeability and modulates pKa of adjacent functional groups, making it valuable in designing potent, selective drugs with improved pharmacokinetic profiles.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿450.00 |
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| 5g | 10-20 days | ฿2,000.00 |
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| 10g | 10-20 days | ฿3,500.00 |
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| 25g | 10-20 days | ฿8,000.00 |
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| 100g | 10-20 days | ฿31,000.00 |
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3-fluoroazetidine hydrochloride
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its strained azetidine ring enhances binding affinity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship optimization, especially in kinase inhibitors and GPCR-targeted agents. The fluorine atom improves membrane permeability and modulates pKa of adjacent functional groups, making it valuable in designing potent, selective drugs with improved pharmacokinetic profiles.
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