1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride
98%
- Product Code: 187830
Alias:
Vili watermelon intermediate; Vilisigua intermediate; Vilisigua intermediate; Leosigua intermediate
CAS:
256499-19-1
| Molecular Weight: | 305.74 g./mol | Molecular Formula: | C₁₄H₁₃ClFN₅ |
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| EC Number: | MDL Number: | MFCD18432772 | |
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| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting JAK (Janus kinase) and other tyrosine kinases involved in inflammatory and autoimmune diseases. Exhibits potential in the development of treatments for conditions such as rheumatoid arthritis, psoriasis, and certain cancers due to its role in modulating signaling pathways. Its structure allows for high selectivity and binding affinity to enzyme active sites, making it valuable in optimizing drug candidates for improved efficacy and reduced off-target effects. Also employed in structure-activity relationship (SAR) studies to enhance metabolic stability and solubility of related compounds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | Ft9,142.20 |
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| 5.000 | 10-20 days | Ft31,314.65 |
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| 25.000 | 10-20 days | Ft117,692.64 |
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1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting JAK (Janus kinase) and other tyrosine kinases involved in inflammatory and autoimmune diseases. Exhibits potential in the development of treatments for conditions such as rheumatoid arthritis, psoriasis, and certain cancers due to its role in modulating signaling pathways. Its structure allows for high selectivity and binding affinity to enzyme active sites, making it valuable in optimizing drug candidates for improved efficacy and reduced off-target effects. Also employed in structure-activity relationship (SAR) studies to enhance metabolic stability and solubility of related compounds.
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