2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
- Product Code: 188059
CAS:
1073353-68-0
| Molecular Weight: | 290.06 g./mol | Molecular Formula: | C₁₃H₁₅BF₄O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08458187 | |
| Melting Point: | Boiling Point: | 288.1±40.0℃ at 760 mmHg | |
| Density: | 1.20±0.1 g/cm3 | Storage Condition: | 2-8℃, sealed, dried |
Product Description:
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for forming carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its stability and reactivity make it ideal for constructing biaryl structures, commonly found in active pharmaceutical ingredients. It is also employed in the development of organic electronic materials due to its ability to introduce fluorinated aromatic groups, which can enhance electron transport properties and thermal stability. The presence of fluorine and trifluoromethyl groups improves metabolic stability in drug candidates, making this reagent valuable in medicinal chemistry for late-stage functionalization.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 1g | 10-20 days | $103.97 |
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| 5g | 10-20 days | $451.42 |
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| 25g | 10-20 days | $2,186.56 |
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2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for forming carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its stability and reactivity make it ideal for constructing biaryl structures, commonly found in active pharmaceutical ingredients. It is also employed in the development of organic electronic materials due to its ability to introduce fluorinated aromatic groups, which can enhance electron transport properties and thermal stability. The presence of fluorine and trifluoromethyl groups improves metabolic stability in drug candidates, making this reagent valuable in medicinal chemistry for late-stage functionalization.
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