5-(3-Fluorophenyl)-1H-tetrazole
98%
- Product Code: 188694
CAS:
50907-20-5
| Molecular Weight: | 164.142 g./mol | Molecular Formula: | C₇H₅FN₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD01075702 | |
| Melting Point: | 142-144 °C | Boiling Point: | 335.5 °C at 760 mmHg |
| Density: | Storage Condition: | Room temperature, seal, dry, inert gas |
Product Description:
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Shows potential in the development of new pharmaceuticals due to its ability to participate in hydrogen bonding and dipole interactions with biological targets.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿750.00 |
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| 1g | 10-20 days | ฿1,680.00 |
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| 5g | 10-20 days | ฿5,600.00 |
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5-(3-Fluorophenyl)-1H-tetrazole
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Shows potential in the development of new pharmaceuticals due to its ability to participate in hydrogen bonding and dipole interactions with biological targets.
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