7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
97%
- Product Code: 188785
CAS:
1394071-77-2
| Molecular Weight: | 261.10 g./mol | Molecular Formula: | C₁₄H₁₇BFNO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09027752 | |
| Melting Point: | Boiling Point: | 391.6±27.0 °C(Predicted) | |
| Density: | 1.16±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed |
Product Description:
Used as a key intermediate in pharmaceutical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl structures. Its indole core with boronate ester functionality enables efficient formation of carbon-carbon bonds, making it valuable in developing drug candidates targeting neurological disorders, inflammation, and cancer. The fluorine substituent enhances binding selectivity and metabolic stability in final active compounds. Commonly employed in research settings for lead optimization in medicinal chemistry programs.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿6,730.00 |
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| 0.250 | 10-20 days | ฿11,410.00 |
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| 1.000 | 10-20 days | ฿32,930.00 |
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7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
Used as a key intermediate in pharmaceutical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl structures. Its indole core with boronate ester functionality enables efficient formation of carbon-carbon bonds, making it valuable in developing drug candidates targeting neurological disorders, inflammation, and cancer. The fluorine substituent enhances binding selectivity and metabolic stability in final active compounds. Commonly employed in research settings for lead optimization in medicinal chemistry programs.
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