Fmoc-4-fluoro-DL-phenylalanine
- Product Code: 188980
CAS:
264276-42-8
| Molecular Weight: | 405.43 g./mol | Molecular Formula: | C₂₄H₂₀FNO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00237667 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in solid-phase peptide synthesis to introduce a fluorinated phenylalanine residue into peptide chains. The Fmoc group allows for mild, base-labile protection of the alpha-amino group, compatible with standard Fmoc-SPPS protocols. The fluorine atom provides a handle for 19F NMR studies, enabling peptide folding, dynamics, and interactions analysis. Commonly applied in the development of bioactive peptides, enzyme inhibitors, and peptide-based probes where aromatic side chain modification influences activity, stability, or binding properties. Its incorporation can enhance metabolic stability and alter lipophilicity, useful in pharmaceutical research and design of peptidomimetics.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | $90.76 |
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Fmoc-4-fluoro-DL-phenylalanine
Used in solid-phase peptide synthesis to introduce a fluorinated phenylalanine residue into peptide chains. The Fmoc group allows for mild, base-labile protection of the alpha-amino group, compatible with standard Fmoc-SPPS protocols. The fluorine atom provides a handle for 19F NMR studies, enabling peptide folding, dynamics, and interactions analysis. Commonly applied in the development of bioactive peptides, enzyme inhibitors, and peptide-based probes where aromatic side chain modification influences activity, stability, or binding properties. Its incorporation can enhance metabolic stability and alter lipophilicity, useful in pharmaceutical research and design of peptidomimetics.
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