4-(Fluorosulfonyl)-1-methyl-1H-pyrrole-2-carboxylic acid
98%
- Product Code: 189099
CAS:
2138238-83-0
| Molecular Weight: | 207.18 g./mol | Molecular Formula: | C₆H₆FNO₄S |
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| Density: | Storage Condition: | -20°C, light-proof, inert gas |
Product Description:
Used as a key intermediate in the synthesis of sulfonyl fluoride-based compounds, particularly in the development of covalent inhibitors for biological targets. Its reactivity allows for selective labeling of proteins and enzymes in chemical biology and proteomics research. Commonly applied in SuFEx (Sulfur-Fluoride Exchange) click chemistry, enabling rapid and stable bond formation under mild conditions. Also utilized in the preparation of pharmacophores for drug discovery, especially in targeting serine hydrolases and other nucleophilic enzyme active sites. Its methyl-protected pyrrole core supports further functionalization, making it valuable in building complex heterocyclic systems for medicinal chemistry.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 100mg | 10-20 days | $233.65 |
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| 250mg | 10-20 days | $387.82 |
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| 1g | 10-20 days | $1,250.09 |
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4-(Fluorosulfonyl)-1-methyl-1H-pyrrole-2-carboxylic acid
Used as a key intermediate in the synthesis of sulfonyl fluoride-based compounds, particularly in the development of covalent inhibitors for biological targets. Its reactivity allows for selective labeling of proteins and enzymes in chemical biology and proteomics research. Commonly applied in SuFEx (Sulfur-Fluoride Exchange) click chemistry, enabling rapid and stable bond formation under mild conditions. Also utilized in the preparation of pharmacophores for drug discovery, especially in targeting serine hydrolases and other nucleophilic enzyme active sites. Its methyl-protected pyrrole core supports further functionalization, making it valuable in building complex heterocyclic systems for medicinal chemistry.
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