2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
- Product Code: 189159
CAS:
445303-67-3
| Molecular Weight: | 290.06 g./mol | Molecular Formula: | C₁₃H₁₅BF₄O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09878544 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for forming carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its fluorinated aryl group enhances the metabolic stability and lipophilicity of target molecules, making it valuable in drug discovery. It is particularly useful in constructing biaryl scaffolds found in bioactive compounds. The presence of trifluoromethyl and fluoro substituents improves electron-withdrawing properties, which can influence the reactivity and binding affinity of the final product. Commonly employed in late-stage functionalization due to its stability and selective coupling ability under mild conditions.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5g | 10-20 days | ฿3,750.00 |
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| 25g | 10-20 days | ฿14,140.00 |
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| 100g | 10-20 days | ฿56,530.00 |
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| 1g | 10-20 days | ฿910.00 |
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2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for forming carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its fluorinated aryl group enhances the metabolic stability and lipophilicity of target molecules, making it valuable in drug discovery. It is particularly useful in constructing biaryl scaffolds found in bioactive compounds. The presence of trifluoromethyl and fluoro substituents improves electron-withdrawing properties, which can influence the reactivity and binding affinity of the final product. Commonly employed in late-stage functionalization due to its stability and selective coupling ability under mild conditions.
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