2-(2-Fluoro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
95%
- Product Code: 189192
CAS:
627526-48-1
| Molecular Weight: | 290.07 g./mol | Molecular Formula: | C₁₃H₁₅BF₄O₂ |
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| EC Number: | MDL Number: | MFCD16996332 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in the development of complex organic molecules, particularly in drug discovery and materials science. The presence of fluorinated substituents enhances reactivity and influences the electronic properties of the final compounds, which is beneficial in designing bioactive molecules with improved metabolic stability and lipophilicity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 1.000 | 10-20 days | $174.88 |
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| 5.000 | 10-20 days | $661.61 |
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| 25.000 | 10-20 days | $2,458.39 |
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| 0.250 | 10-20 days | $65.32 |
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2-(2-Fluoro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in the development of complex organic molecules, particularly in drug discovery and materials science. The presence of fluorinated substituents enhances reactivity and influences the electronic properties of the final compounds, which is beneficial in designing bioactive molecules with improved metabolic stability and lipophilicity.
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