1-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carbonitrile

98%

  • Product Code: 189248
  CAS:    917397-94-5
Molecular Weight: Molecular Formula:
EC Number: MDL Number:
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Density: Storage Condition: 2-8°C, dry
Product Description: Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. The presence of the boronate ester group enables efficient carbon-carbon bond formation under palladium catalysis, making it valuable in constructing complex organic molecules. The cyclopropane-carbonitrile moiety contributes to structural rigidity and metabolic stability, which is beneficial in drug design. Commonly employed in the development of active pharmaceutical ingredients (APIs) where fluorinated aromatic systems are required for enhanced bioavailability and target binding.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days ฿3,830.00
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1g 10-20 days ฿10,550.00
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5g 10-20 days ฿44,910.00
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100mg 10-20 days ฿2,240.00
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1-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carbonitrile
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. The presence of the boronate ester group enables efficient carbon-carbon bond formation under palladium catalysis, making it valuable in constructing complex organic molecules. The cyclopropane-carbonitrile moiety contributes to structural rigidity and metabolic stability, which is beneficial in drug design. Commonly employed in the development of active pharmaceutical ingredients (APIs) where fluorinated aromatic systems are required for enhanced bioavailability and target binding.
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