Fmoc-Phe-Lys(Trt)-PAB-PNP
- Product Code: 189525
CAS:
1116086-09-9
| Molecular Weight: | 1028.15 g./mol | Molecular Formula: | C₆₃H₅₇N₅O₉ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | -20°C |
Product Description:
Used in solid-phase peptide synthesis as a protected amino acid building block, particularly in the preparation of complex peptide sequences for pharmaceutical research. The Fmoc group allows for mild base deprotection, enabling stepwise assembly of peptides. The Trt (trityl) protection on the lysine side chain prevents unwanted reactions during synthesis and can be selectively removed under mild acidic conditions. The PAB-PNP moiety acts as a self-immolative linker, commonly employed in prodrug design and antibody-drug conjugates (ADCs), where it enables controlled release of active agents upon specific triggering, such as enzymatic cleavage. This compound is especially valuable in developing targeted cancer therapies and in bioconjugation strategies requiring high selectivity and stability.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | ฿38,900.00 |
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Fmoc-Phe-Lys(Trt)-PAB-PNP
Used in solid-phase peptide synthesis as a protected amino acid building block, particularly in the preparation of complex peptide sequences for pharmaceutical research. The Fmoc group allows for mild base deprotection, enabling stepwise assembly of peptides. The Trt (trityl) protection on the lysine side chain prevents unwanted reactions during synthesis and can be selectively removed under mild acidic conditions. The PAB-PNP moiety acts as a self-immolative linker, commonly employed in prodrug design and antibody-drug conjugates (ADCs), where it enables controlled release of active agents upon specific triggering, such as enzymatic cleavage. This compound is especially valuable in developing targeted cancer therapies and in bioconjugation strategies requiring high selectivity and stability.
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