1-(4-Fluorophenyl)-5-Methyl-1H-pyrazole-4-carbonylchloride

95%

  • Product Code: 189557
  CAS:    423768-49-4
Molecular Weight: 238.65 g./mol Molecular Formula: C₁₁H₈ClFN₂O
EC Number: MDL Number:
Melting Point: 90-92 °C Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used primarily as an intermediate in the synthesis of pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors. Its structure allows for the introduction of the pyrazole ring system into larger molecules, enhancing biological activity and metabolic stability. Commonly employed in coupling reactions to form amide or ester derivatives for use in medicinal chemistry research. Also utilized in the preparation of agrochemicals and bioactive compounds where fluorinated heterocycles improve lipophilicity and binding affinity.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days $271.79
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1-(4-Fluorophenyl)-5-Methyl-1H-pyrazole-4-carbonylchloride
Used primarily as an intermediate in the synthesis of pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors. Its structure allows for the introduction of the pyrazole ring system into larger molecules, enhancing biological activity and metabolic stability. Commonly employed in coupling reactions to form amide or ester derivatives for use in medicinal chemistry research. Also utilized in the preparation of agrochemicals and bioactive compounds where fluorinated heterocycles improve lipophilicity and binding affinity.
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