8-Fluoroquinoline-5-sulfonylchloride
95%
- Product Code: 189563
CAS:
1000933-89-0
| Molecular Weight: | 245.66 g./mol | Molecular Formula: | C₉H₅ClFNO₂S |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of fluorinated quinoline-based compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group readily reacts with nucleophiles like amines and alcohols, enabling the formation of sulfonamides and sulfonate esters. These derivatives are valuable in drug development for their enhanced bioavailability and metabolic stability. Commonly employed in the preparation of kinase inhibitors and antimicrobial agents due to the combined effects of the fluorine atom and quinoline scaffold. Also utilized in materials science for designing fluorescent probes and sensors, leveraging the electron-withdrawing fluorine and the inherent fluorescence of the quinoline ring.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿8,840.00 |
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8-Fluoroquinoline-5-sulfonylchloride
Used as a key intermediate in the synthesis of fluorinated quinoline-based compounds, particularly in pharmaceuticals and agrochemicals. Its sulfonyl chloride group readily reacts with nucleophiles like amines and alcohols, enabling the formation of sulfonamides and sulfonate esters. These derivatives are valuable in drug development for their enhanced bioavailability and metabolic stability. Commonly employed in the preparation of kinase inhibitors and antimicrobial agents due to the combined effects of the fluorine atom and quinoline scaffold. Also utilized in materials science for designing fluorescent probes and sensors, leveraging the electron-withdrawing fluorine and the inherent fluorescence of the quinoline ring.
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