Fmoc-l-2,4,5-trifluorophenylalanine
95%
- Product Code: 189606
CAS:
959579-81-8
| Molecular Weight: | 441.40 g./mol | Molecular Formula: | C₂₄H₁₈F₃NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD06659142 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in solid-phase peptide synthesis as a protected amino acid building block, particularly for incorporating fluorinated aromatic side chains into peptides. The Fmoc group allows for mild base deprotection, compatible with standard Fmoc/tBu strategies. The trifluorinated phenylalanine derivative enhances peptide stability, lipophilicity, and can influence conformation due to electron-withdrawing effects. Commonly applied in the development of bioactive peptides, enzyme inhibitors, and pharmaceuticals where metabolic resistance and binding affinity are important. Also useful in studying structure-activity relationships in peptide-based research.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | $163.71 |
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| 250mg | 10-20 days | $277.36 |
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| 1g | 10-20 days | $665.58 |
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Fmoc-l-2,4,5-trifluorophenylalanine
Used in solid-phase peptide synthesis as a protected amino acid building block, particularly for incorporating fluorinated aromatic side chains into peptides. The Fmoc group allows for mild base deprotection, compatible with standard Fmoc/tBu strategies. The trifluorinated phenylalanine derivative enhances peptide stability, lipophilicity, and can influence conformation due to electron-withdrawing effects. Commonly applied in the development of bioactive peptides, enzyme inhibitors, and pharmaceuticals where metabolic resistance and binding affinity are important. Also useful in studying structure-activity relationships in peptide-based research.
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