4-fluoro-3-nitrobenzene-1-sulfonyl fluoride
≥95%
- Product Code: 189750
CAS:
500585-16-0
| Molecular Weight: | 223.15 g./mol | Molecular Formula: | C₆H₃F₂NO₄S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD07777175 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a highly reactive electrophilic reagent in organic synthesis, particularly in the development of covalent inhibitors for biological targets. Its sulfonyl fluoride group reacts selectively with nucleophilic amino acid residues such as serine, threonine, and lysine in proteins, making it valuable in chemical biology for activity-based protein profiling (ABPP). The presence of the fluorine and nitro groups enhances its reactivity and allows for further functionalization via cross-coupling or reduction reactions. Commonly employed in the design of probes and pharmaceuticals where targeted covalent modification is desired. Also utilized in materials science for surface modification due to its ability to form stable covalent bonds with hydroxyl or amine groups on substrates.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿17,840.00 |
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4-fluoro-3-nitrobenzene-1-sulfonyl fluoride
Used as a highly reactive electrophilic reagent in organic synthesis, particularly in the development of covalent inhibitors for biological targets. Its sulfonyl fluoride group reacts selectively with nucleophilic amino acid residues such as serine, threonine, and lysine in proteins, making it valuable in chemical biology for activity-based protein profiling (ABPP). The presence of the fluorine and nitro groups enhances its reactivity and allows for further functionalization via cross-coupling or reduction reactions. Commonly employed in the design of probes and pharmaceuticals where targeted covalent modification is desired. Also utilized in materials science for surface modification due to its ability to form stable covalent bonds with hydroxyl or amine groups on substrates.
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