Fmoc-PNA-A(Bhoc)-OH

≥98%(HPLC)

  • Product Code: 189769
  CAS:    186046-82-2
Molecular Weight: 725.76 g./mol Molecular Formula: C₄₀H₃₅N₇O₇
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20°C
Product Description: Used in solid-phase peptide synthesis, this compound enables the controlled assembly of peptide nucleic acid (PNA) sequences with high fidelity. The Fmoc group allows for orthogonal protection strategies, facilitating stepwise chain elongation in automated synthesizers. The Bhoc protecting group on the adenine base prevents unwanted side reactions during coupling, ensuring clean deprotection under mild acidic conditions. Its primary application lies in the production of PNA oligomers for research in molecular biology, including gene regulation studies, antisense technology, and development of nucleic acid diagnostics. The compound is also valuable in creating PNA probes for detecting specific DNA or RNA sequences due to PNA's strong and selective binding properties.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $158.08
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-
250mg 10-20 days $328.89
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-
1g 10-20 days $1,000.45
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Fmoc-PNA-A(Bhoc)-OH
Used in solid-phase peptide synthesis, this compound enables the controlled assembly of peptide nucleic acid (PNA) sequences with high fidelity. The Fmoc group allows for orthogonal protection strategies, facilitating stepwise chain elongation in automated synthesizers. The Bhoc protecting group on the adenine base prevents unwanted side reactions during coupling, ensuring clean deprotection under mild acidic conditions. Its primary application lies in the production of PNA oligomers for research in molecular biology, including gene regulation studies, antisense technology, and development of nucleic acid diagnostics. The compound is also valuable in creating PNA probes for detecting specific DNA or RNA sequences due to PNA's strong and selective binding properties.
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