GNE-317
10mM in DMSO
- Product Code: 190081
CAS:
1394076-92-6
Molecular Weight: | 414.48 g./mol | Molecular Formula: | C₁₉H₂₂N₆O₃S |
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Density: | Storage Condition: | -20°C |
Product Description:
GNE-317 is an investigational small molecule inhibitor primarily studied for its potential in cancer therapy. It targets the PI3K/AKT/mTOR signaling pathway, which is frequently dysregulated in various tumors. By inhibiting key kinases in this pathway, GNE-317 helps suppress tumor cell proliferation and survival. It has shown activity against brain-penetrant tumor models, making it particularly relevant for the treatment of central nervous system (CNS) malignancies, including glioblastoma and brain metastases. Due to its ability to cross the blood-brain barrier, GNE-317 is being explored in preclinical and early clinical settings as a promising agent for hard-to-treat neurological cancers. Its development supports efforts to create more effective, targeted therapies with improved CNS exposure.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1ml | 10-20 days | ฿6,480.00 |
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GNE-317
GNE-317 is an investigational small molecule inhibitor primarily studied for its potential in cancer therapy. It targets the PI3K/AKT/mTOR signaling pathway, which is frequently dysregulated in various tumors. By inhibiting key kinases in this pathway, GNE-317 helps suppress tumor cell proliferation and survival. It has shown activity against brain-penetrant tumor models, making it particularly relevant for the treatment of central nervous system (CNS) malignancies, including glioblastoma and brain metastases. Due to its ability to cross the blood-brain barrier, GNE-317 is being explored in preclinical and early clinical settings as a promising agent for hard-to-treat neurological cancers. Its development supports efforts to create more effective, targeted therapies with improved CNS exposure.
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