GDC-0326
10mM in DMSO
- Product Code: 190090
CAS:
1282514-88-8
| Molecular Weight: | 382.42 g./mol | Molecular Formula: | C₁₉H₂₂N₆O₃ |
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| Density: | Storage Condition: | -20°C |
Product Description:
GDC-0326 is primarily used in research settings for its potent and selective inhibition of BTK (Bruton's tyrosine kinase). It is designed to target both wild-type and C481S-mutant forms of BTK, making it valuable in studying resistance mechanisms in B-cell malignancies. Its application is especially relevant in the development of therapies for cancers such as chronic lymphocytic leukemia and non-Hodgkin’s lymphoma. Due to its irreversible binding mechanism, GDC-0326 enables sustained suppression of BTK signaling, which helps in evaluating long-term pathway inhibition in preclinical models. It is not intended for clinical use but serves as a critical tool compound in oncology and immunology research.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | $257.49 |
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GDC-0326
GDC-0326 is primarily used in research settings for its potent and selective inhibition of BTK (Bruton's tyrosine kinase). It is designed to target both wild-type and C481S-mutant forms of BTK, making it valuable in studying resistance mechanisms in B-cell malignancies. Its application is especially relevant in the development of therapies for cancers such as chronic lymphocytic leukemia and non-Hodgkin’s lymphoma. Due to its irreversible binding mechanism, GDC-0326 enables sustained suppression of BTK signaling, which helps in evaluating long-term pathway inhibition in preclinical models. It is not intended for clinical use but serves as a critical tool compound in oncology and immunology research.
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