GS-9620
2mM in DMSO
- Product Code: 190177
CAS:
1228585-88-3
| Molecular Weight: | 410.51 g./mol | Molecular Formula: | C₂₂H₃₀N₆O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD25372045 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
GS-9620 is a potent agonist of toll-like receptor 7 (TLR7), primarily investigated for its ability to activate the innate immune system. It has been studied extensively in the context of chronic viral infections, particularly hepatitis B virus (HBV). By stimulating TLR7 in immune cells such as plasmacytoid dendritic cells, GS-9620 induces the production of antiviral cytokines, including interferon-alpha, which helps enhance the body’s immune response against the virus.
Its application focuses on achieving functional cure in chronic HBV infection by reducing levels of hepatitis B surface antigen (HBsAg) and promoting immune control of the virus. Due to its oral bioavailability, GS-9620 offers a convenient dosing regimen compared to injectable interferon therapies, making it a candidate for combination treatment strategies with antivirals or therapeutic vaccines. Research has also explored its potential in oncology and other infectious diseases where immune activation may provide therapeutic benefit.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿1,850.00 |
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GS-9620
GS-9620 is a potent agonist of toll-like receptor 7 (TLR7), primarily investigated for its ability to activate the innate immune system. It has been studied extensively in the context of chronic viral infections, particularly hepatitis B virus (HBV). By stimulating TLR7 in immune cells such as plasmacytoid dendritic cells, GS-9620 induces the production of antiviral cytokines, including interferon-alpha, which helps enhance the body’s immune response against the virus.
Its application focuses on achieving functional cure in chronic HBV infection by reducing levels of hepatitis B surface antigen (HBsAg) and promoting immune control of the virus. Due to its oral bioavailability, GS-9620 offers a convenient dosing regimen compared to injectable interferon therapies, making it a candidate for combination treatment strategies with antivirals or therapeutic vaccines. Research has also explored its potential in oncology and other infectious diseases where immune activation may provide therapeutic benefit.
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