GSK503
10mM in DMSO
- Product Code: 190179
CAS:
1346572-63-1
| Molecular Weight: | 526.67 g./mol | Molecular Formula: | C₃₁H₃₈N₆O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28405142 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
GSK503 is primarily used as a potent and selective inhibitor of the EZH2 enzyme, which plays a key role in epigenetic regulation. It is widely applied in cancer research, especially in studies involving tumors with EZH2 gain-of-function mutations, such as certain lymphomas. By inhibiting EZH2, GSK503 reduces abnormal histone methylation, leading to reactivation of tumor suppressor genes. This makes it a valuable tool in developing targeted therapies for hematological malignancies and other cancers driven by epigenetic dysregulation. It is also used in preclinical models to study chromatin dynamics and gene expression control.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿8,000.00 |
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GSK503
GSK503 is primarily used as a potent and selective inhibitor of the EZH2 enzyme, which plays a key role in epigenetic regulation. It is widely applied in cancer research, especially in studies involving tumors with EZH2 gain-of-function mutations, such as certain lymphomas. By inhibiting EZH2, GSK503 reduces abnormal histone methylation, leading to reactivation of tumor suppressor genes. This makes it a valuable tool in developing targeted therapies for hematological malignancies and other cancers driven by epigenetic dysregulation. It is also used in preclinical models to study chromatin dynamics and gene expression control.
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