GSK481
10mM in DMSO
- Product Code: 190188
CAS:
1622849-58-4
| Molecular Weight: | 377.39 g./mol | Molecular Formula: | C₂₁H₁₉N₃O₄ |
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| Density: | Storage Condition: | -20°C |
Product Description:
GSK481 is primarily used in pharmaceutical research as a potent and selective inhibitor of the enzyme PI3Kδ (phosphoinositide 3-kinase delta). This enzyme plays a key role in immune cell signaling, making GSK481 a valuable tool in studying inflammatory and autoimmune diseases such as rheumatoid arthritis, asthma, and lupus. It has also shown potential in oncology research, particularly in B-cell malignancies like chronic lymphocytic leukemia, where PI3Kδ signaling contributes to tumor cell survival and proliferation. Due to its high selectivity, GSK481 helps minimize off-target effects in experimental models, supporting its use in preclinical studies to validate PI3Kδ as a therapeutic target.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,200.00 |
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GSK481
GSK481 is primarily used in pharmaceutical research as a potent and selective inhibitor of the enzyme PI3Kδ (phosphoinositide 3-kinase delta). This enzyme plays a key role in immune cell signaling, making GSK481 a valuable tool in studying inflammatory and autoimmune diseases such as rheumatoid arthritis, asthma, and lupus. It has also shown potential in oncology research, particularly in B-cell malignancies like chronic lymphocytic leukemia, where PI3Kδ signaling contributes to tumor cell survival and proliferation. Due to its high selectivity, GSK481 helps minimize off-target effects in experimental models, supporting its use in preclinical studies to validate PI3Kδ as a therapeutic target.
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