GSK-2126458
10mM in DMSO
- Product Code: 190212
CAS:
1086062-66-9
| Molecular Weight: | 505.50 g./mol | Molecular Formula: | C₂₅H₁₇F₂N₅O₃S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 187-189 °C | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in research settings as a potent inhibitor of PI3K (phosphoinositide 3-kinase) and mTOR (mammalian target of rapamycin) pathways. These pathways are involved in cell growth, survival, and proliferation, making this compound valuable in studying cancer cell signaling. It has been investigated for its antitumor activity in various preclinical models, particularly in cancers with dysregulated PI3K/mTOR signaling. Due to its ability to cross the blood-brain barrier in experimental models, it is also explored for central nervous system malignancies. Not approved for clinical use and strictly limited to laboratory research.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿4,840.00 |
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GSK-2126458
Used primarily in research settings as a potent inhibitor of PI3K (phosphoinositide 3-kinase) and mTOR (mammalian target of rapamycin) pathways. These pathways are involved in cell growth, survival, and proliferation, making this compound valuable in studying cancer cell signaling. It has been investigated for its antitumor activity in various preclinical models, particularly in cancers with dysregulated PI3K/mTOR signaling. Due to its ability to cross the blood-brain barrier in experimental models, it is also explored for central nervous system malignancies. Not approved for clinical use and strictly limited to laboratory research.
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