Gap 27
10mM in DMSO
- Product Code: 190230
CAS:
198284-64-9
| Molecular Weight: | 1304.53(free) g./mol | Molecular Formula: | C₆₀H₁₀₁N₁₅O₁₇(free） |
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| Density: | Storage Condition: | -20°C |
Product Description:
Gap 27 is widely used in research settings to study cell communication and signaling pathways, particularly those involving gap junctions. It acts as an inhibitor of gap junction intercellular communication (GJIC), making it a valuable tool for investigating the role of connexin channels in processes such as cell proliferation, differentiation, and tissue homeostasis. Researchers apply Gap 27 in studies related to cancer biology, where disrupted cell communication contributes to tumor progression, allowing them to assess how blocking connexin function affects tumor cell behavior. It is also used in cardiovascular research to explore the impact of gap junction modulation on heart tissue, especially in arrhythmias and ischemic conditions. Additionally, Gap 27 has been employed in neuroscience to examine glial cell interactions and neuronal synchronization. Due to its ability to specifically target connexin 43-mediated channels, it supports targeted experiments in inflammation, wound healing, and developmental biology.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,500.00 |
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Gap 27
Gap 27 is widely used in research settings to study cell communication and signaling pathways, particularly those involving gap junctions. It acts as an inhibitor of gap junction intercellular communication (GJIC), making it a valuable tool for investigating the role of connexin channels in processes such as cell proliferation, differentiation, and tissue homeostasis. Researchers apply Gap 27 in studies related to cancer biology, where disrupted cell communication contributes to tumor progression, allowing them to assess how blocking connexin function affects tumor cell behavior. It is also used in cardiovascular research to explore the impact of gap junction modulation on heart tissue, especially in arrhythmias and ischemic conditions. Additionally, Gap 27 has been employed in neuroscience to examine glial cell interactions and neuronal synchronization. Due to its ability to specifically target connexin 43-mediated channels, it supports targeted experiments in inflammation, wound healing, and developmental biology.
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