GZD824 Dimesylate
98%
- Product Code: 190892
CAS:
1421783-64-3
| Molecular Weight: | 724.77 g./mol | Molecular Formula: | C₂₉H₂₇F₃N₆O·₂CH₄O₃S |
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| Density: | Storage Condition: | -20°C, avoiding light |
Product Description:
GZD824 Dimesylate is a potent inhibitor of BCR-ABL tyrosine kinase, including the T315I mutant form, which is commonly associated with resistance to other kinase inhibitors in chronic myeloid leukemia (CML). It is primarily used in research settings for the development of targeted therapies against CML and other hematological malignancies driven by ABL kinase activity. Due to its high selectivity and efficacy in overcoming drug resistance, GZD824 Dimesylate serves as a valuable tool compound in preclinical studies evaluating signaling pathways and resistance mechanisms in leukemia cells. It has shown strong antiproliferative effects in cell-based assays and has demonstrated tumor growth inhibition in animal models of CML, supporting its potential as a therapeutic candidate in oncology drug development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 G | 10-20 days | ฿5,950.00 |
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GZD824 Dimesylate
GZD824 Dimesylate is a potent inhibitor of BCR-ABL tyrosine kinase, including the T315I mutant form, which is commonly associated with resistance to other kinase inhibitors in chronic myeloid leukemia (CML). It is primarily used in research settings for the development of targeted therapies against CML and other hematological malignancies driven by ABL kinase activity. Due to its high selectivity and efficacy in overcoming drug resistance, GZD824 Dimesylate serves as a valuable tool compound in preclinical studies evaluating signaling pathways and resistance mechanisms in leukemia cells. It has shown strong antiproliferative effects in cell-based assays and has demonstrated tumor growth inhibition in animal models of CML, supporting its potential as a therapeutic candidate in oncology drug development.
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