GSK2798745
99%
- Product Code: 190928
CAS:
1419609-94-1
| Molecular Weight: | 460.53 g./mol | Molecular Formula: | C₂₅H₂₈N₆O₃ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in clinical research for the treatment of hypertension and heart failure, GSK2798745 acts as a selective antagonist of the endothelin receptor A (ETA). It helps reduce vasoconstriction and vascular remodeling by blocking the action of endothelin-1, a potent vasoconstrictor peptide. This mechanism supports improved blood flow and reduced cardiac workload. The compound has been investigated for its potential to alleviate symptoms in patients with resistant hypertension and chronic kidney disease, where endothelin system overactivity is implicated. Studies also explore its role in pulmonary arterial hypertension and other cardiovascular conditions involving endothelial dysfunction.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 G | 10-20 days | ฿69,510.00 |
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GSK2798745
Used in clinical research for the treatment of hypertension and heart failure, GSK2798745 acts as a selective antagonist of the endothelin receptor A (ETA). It helps reduce vasoconstriction and vascular remodeling by blocking the action of endothelin-1, a potent vasoconstrictor peptide. This mechanism supports improved blood flow and reduced cardiac workload. The compound has been investigated for its potential to alleviate symptoms in patients with resistant hypertension and chronic kidney disease, where endothelin system overactivity is implicated. Studies also explore its role in pulmonary arterial hypertension and other cardiovascular conditions involving endothelial dysfunction.
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