10-(2-(1H-Tetrazol-5-yl)ethyl)-2,7-dichloro-9,9-dimethyl-9,10-dihydroacridine
98%
- Product Code: 191253
CAS:
1443290-89-8
| Molecular Weight: | 374.27 g./mol | Molecular Formula: | C₁₈H₁₇Cl₂N₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32215313 | |
| Melting Point: | Boiling Point: | 586.8±60.0 °C(Predicted) | |
| Density: | 1.357±0.06 g/cm3(Predicted) | Storage Condition: | -20°C, Inert Gas |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of antihypertensive drugs. Its tetrazole moiety enhances bioavailability and mimics the carboxylic acid group in drug molecules, improving binding affinity to target receptors. Commonly employed in the preparation of sartan-class medications, where it contributes to the structural framework that blocks vasoconstriction and aldosterone release, helping manage high blood pressure. Also explored in medicinal chemistry for optimizing metabolic stability and pharmacokinetic profiles of new drug candidates.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿33,280.00 |
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| 0.250 G | 10-20 days | ฿56,570.00 |
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10-(2-(1H-Tetrazol-5-yl)ethyl)-2,7-dichloro-9,9-dimethyl-9,10-dihydroacridine
Used in pharmaceutical research as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of antihypertensive drugs. Its tetrazole moiety enhances bioavailability and mimics the carboxylic acid group in drug molecules, improving binding affinity to target receptors. Commonly employed in the preparation of sartan-class medications, where it contributes to the structural framework that blocks vasoconstriction and aldosterone release, helping manage high blood pressure. Also explored in medicinal chemistry for optimizing metabolic stability and pharmacokinetic profiles of new drug candidates.
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