2-(1H-imidazol-1-yl)-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-5H-pyrrolo[3,2-d]pyrimidine-4-carboxamide
98%
- Product Code: 191377
CAS:
2597933-17-8
| Molecular Weight: | 384.43 g./mol | Molecular Formula: | C₁₉H₂₄N₆O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD34686586 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.43±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, light-proof, inert gas |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), this compound shows promise in the treatment of autoimmune diseases such as rheumatoid arthritis, lupus, and multiple sclerosis. By blocking BTK activity, it modulates B-cell receptor signaling, reducing the activation of immune cells involved in inflammatory responses. It is also being investigated for oncology applications, particularly in B-cell malignancies like chronic lymphocytic leukemia and mantle cell lymphoma, where BTK plays a key role in cancer cell survival and proliferation. Its structural design allows for improved selectivity and reduced off-target effects, making it a candidate for oral administration in long-term therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 G | 10-20 days | ฿9,050.00 |
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| 0.050 G | 10-20 days | ฿15,370.00 |
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| 0.100 G | 10-20 days | ฿26,120.00 |
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2-(1H-imidazol-1-yl)-N-((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)-5H-pyrrolo[3,2-d]pyrimidine-4-carboxamide
Used in pharmaceutical research as a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), this compound shows promise in the treatment of autoimmune diseases such as rheumatoid arthritis, lupus, and multiple sclerosis. By blocking BTK activity, it modulates B-cell receptor signaling, reducing the activation of immune cells involved in inflammatory responses. It is also being investigated for oncology applications, particularly in B-cell malignancies like chronic lymphocytic leukemia and mantle cell lymphoma, where BTK plays a key role in cancer cell survival and proliferation. Its structural design allows for improved selectivity and reduced off-target effects, making it a candidate for oral administration in long-term therapies.
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