Hydroxy-PEG3-SS-PEG3-alcohol
98%
- Product Code: 191741
CAS:
5662-81-7
| Molecular Weight: | 418.57 g./mol | Molecular Formula: | C₁₆H₃₄O₈S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28976684 | |
| Melting Point: | Boiling Point: | 533.6±50.0 °C(Predicted) | |
| Density: | 1.183±0.06 g/cm3(Predicted) | Storage Condition: | -20°C |
Product Description:
Used in bioconjugation and drug delivery systems due to its bifunctional structure with a cleavable disulfide linker. The hydroxy and alcohol termini allow for stepwise coupling with active molecules, while the PEG spacers enhance solubility and reduce aggregation. Commonly employed in the synthesis of antibody-drug conjugates (ADCs) and targeted therapies where controlled release is required. The disulfide bond is stable in circulation but cleaved in reducing environments such as the cytoplasm, enabling site-specific payload release. Also applied in PEGylation strategies to improve pharmacokinetics of peptides and small molecules.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿79,980.00 |
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Hydroxy-PEG3-SS-PEG3-alcohol
Used in bioconjugation and drug delivery systems due to its bifunctional structure with a cleavable disulfide linker. The hydroxy and alcohol termini allow for stepwise coupling with active molecules, while the PEG spacers enhance solubility and reduce aggregation. Commonly employed in the synthesis of antibody-drug conjugates (ADCs) and targeted therapies where controlled release is required. The disulfide bond is stable in circulation but cleaved in reducing environments such as the cytoplasm, enabling site-specific payload release. Also applied in PEGylation strategies to improve pharmacokinetics of peptides and small molecules.
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