(4-(1H-Tetrazol-5-yl)phenyl)methanol
95%
- Product Code: 191790
CAS:
501126-02-9
| Molecular Weight: | 176.18 g./mol | Molecular Formula: | C₈H₈N₄O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09909570 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical synthesis as an intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like valsartan and losartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving drug efficacy. The hydroxymethyl group allows further functionalization, enabling chemical modifications to optimize pharmacokinetic properties. Also employed in research for developing new bioactive molecules due to the metabolic stability and polarity provided by the tetrazole ring.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 G | 10-20 days | ฿21,600.00 |
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(4-(1H-Tetrazol-5-yl)phenyl)methanol
Used in pharmaceutical synthesis as an intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like valsartan and losartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving drug efficacy. The hydroxymethyl group allows further functionalization, enabling chemical modifications to optimize pharmacokinetic properties. Also employed in research for developing new bioactive molecules due to the metabolic stability and polarity provided by the tetrazole ring.
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