2-(1-(ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile
98%
- Product Code: 192076
CAS:
1187594-13-3
| Molecular Weight: | 501.68 g./mol | Molecular Formula: | C₂₂H₃₁N₇O₃SSi |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of targeted cancer therapies, particularly kinase inhibitors. Its structure supports binding to specific enzyme active sites, making it valuable in developing drugs that modulate signaling pathways in tumor cells. The presence of functional groups like the sulfonyl and nitrile moieties enhances binding affinity and selectivity. It is also employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved metabolic stability and potency. Commonly used in late-stage functionalization during preclinical development of oncology compounds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 G | 10-20 days | ฿48,000.00 |
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2-(1-(ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile
Used in pharmaceutical research as a key intermediate in the synthesis of targeted cancer therapies, particularly kinase inhibitors. Its structure supports binding to specific enzyme active sites, making it valuable in developing drugs that modulate signaling pathways in tumor cells. The presence of functional groups like the sulfonyl and nitrile moieties enhances binding affinity and selectivity. It is also employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved metabolic stability and potency. Commonly used in late-stage functionalization during preclinical development of oncology compounds.
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