(3-Hydrazinocarbonyl-bicyclo[1.1.1]pent-1-yl)-carbamic acid tert-butyl ester
97%
- Product Code: 192104
CAS:
2278281-83-5
| Molecular Weight: | 241.29 g./mol | Molecular Formula: | C₁₁H₁₉N₃O₃ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of targeted protein degraders, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). Its rigid bicyclic structure enables efficient linker design between an E3 ligase ligand and a target protein binder, enhancing binding selectivity and cellular permeability. The hydrazide and Boc-protected amine functionalities allow for selective conjugation under mild conditions, making it valuable in medicinal chemistry for constructing complex bifunctional molecules. Commonly employed in research settings for optimizing degradation efficiency and pharmacokinetic properties of novel therapeutics.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿20,000.00 |
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(3-Hydrazinocarbonyl-bicyclo[1.1.1]pent-1-yl)-carbamic acid tert-butyl ester
Used as a key intermediate in the synthesis of targeted protein degraders, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). Its rigid bicyclic structure enables efficient linker design between an E3 ligase ligand and a target protein binder, enhancing binding selectivity and cellular permeability. The hydrazide and Boc-protected amine functionalities allow for selective conjugation under mild conditions, making it valuable in medicinal chemistry for constructing complex bifunctional molecules. Commonly employed in research settings for optimizing degradation efficiency and pharmacokinetic properties of novel therapeutics.
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