6-Chloro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
98%
- Product Code: 192114
CAS:
2374152-83-5
| Molecular Weight: | 376.69 g./mol | Molecular Formula: | C₁₉H₂₆BClN₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD33398825 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex indazole derivatives with potential biological activity. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other bioactive molecules. The tetrahydropyranyl (THP) protecting group enhances stability and solubility during synthetic transformations, allowing selective deprotection under mild acidic conditions. This compound is primarily employed in late-stage functionalization of drug candidates to explore structure-activity relationships.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿11,150.00 |
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| 0.250 G | 10-20 days | ฿18,610.00 |
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6-Chloro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex indazole derivatives with potential biological activity. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other bioactive molecules. The tetrahydropyranyl (THP) protecting group enhances stability and solubility during synthetic transformations, allowing selective deprotection under mild acidic conditions. This compound is primarily employed in late-stage functionalization of drug candidates to explore structure-activity relationships.
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