1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
98%
- Product Code: 192243
CAS:
350678-63-6
| Molecular Weight: | 405.42 g./mol | Molecular Formula: | C₂₃H₂₀FN₃O₃ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 665.1±55.0 °C(Predicted) | |
| Density: | 1.30±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used in pharmaceutical research as a potent inhibitor of cytochrome P450 enzymes, particularly CYP3A4, this compound serves as a lead structure in developing agents that modulate drug metabolism. Its ability to selectively bind and inhibit key metabolic enzymes makes it valuable in enhancing the bioavailability of co-administered drugs. It has also shown potential in studies targeting hormone-dependent conditions due to its interaction with steroidogenic pathways. Additionally, its structural features support investigation in central nervous system disorders, where enzyme inhibition may influence neurochemical balance. Research applications include in vitro assays, metabolic stability tests, and pharmacokinetic enhancement strategies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 G | 10-20 days | ฿10,990.00 |
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| 0.025 G | 10-20 days | ฿28,590.00 |
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1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
Used in pharmaceutical research as a potent inhibitor of cytochrome P450 enzymes, particularly CYP3A4, this compound serves as a lead structure in developing agents that modulate drug metabolism. Its ability to selectively bind and inhibit key metabolic enzymes makes it valuable in enhancing the bioavailability of co-administered drugs. It has also shown potential in studies targeting hormone-dependent conditions due to its interaction with steroidogenic pathways. Additionally, its structural features support investigation in central nervous system disorders, where enzyme inhibition may influence neurochemical balance. Research applications include in vitro assays, metabolic stability tests, and pharmacokinetic enhancement strategies.
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