4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride
97%
- Product Code: 192282
CAS:
924964-20-5
Molecular Weight: | 244.66 g./mol | Molecular Formula: | C₇H₅ClN₄O₂S |
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EC Number: | MDL Number: | MFCD18432765 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | 2-8°C |
Product Description:
Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1.000 G | 10-20 days | ฿33,000.00 |
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4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride
Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.
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