4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride

97%

  • Product Code: 192282
  CAS:    924964-20-5
Molecular Weight: 244.66 g./mol Molecular Formula: C₇H₅ClN₄O₂S
EC Number: MDL Number: MFCD18432765
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1.000 G 10-20 days ฿33,000.00
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4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride
Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.
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