2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde
95%
- Product Code: 192294
CAS:
151052-40-3
Molecular Weight: | 250.26 g./mol | Molecular Formula: | C₁₄H₁₀N₄O |
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EC Number: | MDL Number: | MFCD20483409 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20°C, Inert Gas |
Product Description:
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole group mimics the carboxylate moiety of angiotensin II, enabling effective binding to the AT1 receptor. This compound plays a critical role in enhancing the potency and metabolic stability of these medications. It is widely utilized in pharmaceutical research and development for cardiovascular therapies.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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0.025 G | 10-20 days | ฿21,900.00 |
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2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole group mimics the carboxylate moiety of angiotensin II, enabling effective binding to the AT1 receptor. This compound plays a critical role in enhancing the potency and metabolic stability of these medications. It is widely utilized in pharmaceutical research and development for cardiovascular therapies.
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