6-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole
95%
- Product Code: 192321
CAS:
2407852-20-2
| Molecular Weight: | 404.38 g./mol | Molecular Formula: | C₂₀H₃₃BN₂O₄Si |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 493.1±45.0 °C(Predicted) | |
| Density: | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex indazole derivatives. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other bioactive molecules. The SEM protecting group on the indazole nitrogen ensures stability during reactions and can be selectively removed under mild acidic conditions, allowing for further functionalization. This compound is especially useful in medicinal chemistry for constructing libraries of heterocyclic compounds in drug discovery programs.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿9,250.00 |
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| 1.000 G | 10-20 days | ฿24,000.00 |
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6-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex indazole derivatives. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other bioactive molecules. The SEM protecting group on the indazole nitrogen ensures stability during reactions and can be selectively removed under mild acidic conditions, allowing for further functionalization. This compound is especially useful in medicinal chemistry for constructing libraries of heterocyclic compounds in drug discovery programs.
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