2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
97%
- Product Code: 192388
CAS:
2138226-21-6
| Molecular Weight: | 399.44 g./mol | Molecular Formula: | C₂₅H₂₁NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31421834 | |
| Melting Point: | Boiling Point: | 622.0±55.0 °C(Predicted) | |
| Density: | 1.323±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Widely used in peptide synthesis as a protected building block, this compound enables selective amine protection through the Fmoc group. It is especially valuable in solid-phase peptide synthesis (SPPS), where the Fmoc strategy is employed for stepwise assembly of peptides. The carboxylic acid functionality allows for coupling to amino acid chains, while the Fmoc group provides temporary protection of the amine, which can be cleanly removed under mild basic conditions without affecting other sensitive functional groups. Its rigid tetrahydroisoquinoline scaffold also helps influence conformation and improve coupling efficiency in complex peptide sequences. Commonly used in the preparation of biologically active peptides, peptidomimetics, and pharmaceutical intermediates.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿14,100.00 |
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| 0.250 G | 10-20 days | ฿23,960.00 |
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2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
Widely used in peptide synthesis as a protected building block, this compound enables selective amine protection through the Fmoc group. It is especially valuable in solid-phase peptide synthesis (SPPS), where the Fmoc strategy is employed for stepwise assembly of peptides. The carboxylic acid functionality allows for coupling to amino acid chains, while the Fmoc group provides temporary protection of the amine, which can be cleanly removed under mild basic conditions without affecting other sensitive functional groups. Its rigid tetrahydroisoquinoline scaffold also helps influence conformation and improve coupling efficiency in complex peptide sequences. Commonly used in the preparation of biologically active peptides, peptidomimetics, and pharmaceutical intermediates.
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