(4-Chloro-1-methyl-1H-indol-2-yl)boronic acid
95%
- Product Code: 192408
CAS:
912331-32-9
| Molecular Weight: | 209.44 g./mol | Molecular Formula: | C₉H₉BClNO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18427579 | |
| Melting Point: | Boiling Point: | 433.6±48.0 °C(Predicted) | |
| Density: | 1.31±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Inert Gas |
Product Description:
Used in organic synthesis as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical development. Its boronic acid group facilitates palladium-catalyzed coupling with aryl halides, making it valuable in constructing complex indole derivatives. These derivatives are often found in bioactive molecules, including drug candidates targeting neurological disorders and inflammation. The presence of the chloro and methyl substituents on the indole ring influences reactivity and selectivity, allowing for selective functionalization in multi-step syntheses. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿4,990.00 |
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| 0.100 G | 10-20 days | ฿2,900.00 |
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(4-Chloro-1-methyl-1H-indol-2-yl)boronic acid
Used in organic synthesis as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical development. Its boronic acid group facilitates palladium-catalyzed coupling with aryl halides, making it valuable in constructing complex indole derivatives. These derivatives are often found in bioactive molecules, including drug candidates targeting neurological disorders and inflammation. The presence of the chloro and methyl substituents on the indole ring influences reactivity and selectivity, allowing for selective functionalization in multi-step syntheses. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.
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