4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine
98%
- Product Code: 192438
CAS:
2189684-53-3
| Molecular Weight: | 375.58 g./mol | Molecular Formula: | C₁₅H₁₈BClF₃N₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD34471206 | |
| Melting Point: | Boiling Point: | 462.5±45.0 °C(Predicted) | |
| Density: | 1.39±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, light-proof, inert gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active indazole derivatives. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other targeted therapies. The trifluoroethyl and chloro substituents enhance reactivity and selectivity in coupling processes, allowing for the construction of complex molecular architectures found in drug candidates. Commonly employed in medicinal chemistry for lead optimization and library synthesis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿1,330.00 |
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| 0.250 G | 10-20 days | ฿2,660.00 |
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| 1.000 G | 10-20 days | ฿4,370.00 |
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4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active indazole derivatives. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in pharmaceutical research, particularly in the development of kinase inhibitors and other targeted therapies. The trifluoroethyl and chloro substituents enhance reactivity and selectivity in coupling processes, allowing for the construction of complex molecular architectures found in drug candidates. Commonly employed in medicinal chemistry for lead optimization and library synthesis.
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