(1-(tert-Butyldimethylsilyl)-1H-indol-4-yl)boronic acid
≥98%
- Product Code: 192502
CAS:
351457-64-2
| Molecular Weight: | 275.23 g./mol | Molecular Formula: | C₁₄H₂₂BNO₂Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08436007 | |
| Melting Point: | 130-135 °C | Boiling Point: | 352.1±48.0 °C(Predicted) |
| Density: | 1.01±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Inert Gas |
Product Description:
Used primarily as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions. It enables the formation of biaryl compounds by coupling with aryl halides, making it valuable in pharmaceutical and agrochemical research. The indole scaffold is common in bioactive molecules, and the presence of the boronic acid group allows for efficient carbon-carbon bond formation. The tert-butyldimethylsilyl (TBS) protecting group stabilizes the indole nitrogen during reactions, ensuring selectivity and compatibility with multi-step synthetic sequences. Commonly employed in the development of drug candidates targeting neurological disorders, inflammation, and cancer.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿3,260.00 |
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| 1.000 G | 10-20 days | ฿9,310.00 |
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(1-(tert-Butyldimethylsilyl)-1H-indol-4-yl)boronic acid
Used primarily as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions. It enables the formation of biaryl compounds by coupling with aryl halides, making it valuable in pharmaceutical and agrochemical research. The indole scaffold is common in bioactive molecules, and the presence of the boronic acid group allows for efficient carbon-carbon bond formation. The tert-butyldimethylsilyl (TBS) protecting group stabilizes the indole nitrogen during reactions, ensuring selectivity and compatibility with multi-step synthetic sequences. Commonly employed in the development of drug candidates targeting neurological disorders, inflammation, and cancer.
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