tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl)carbamate
98%
- Product Code: 192529
CAS:
1338547-17-3
| Molecular Weight: | 359.27 g./mol | Molecular Formula: | C₂₀H₃₀BNO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD16987837 | |
| Melting Point: | Boiling Point: | 477.4±45.0 °C(Predicted) | |
| Density: | 1.09±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used primarily in organic synthesis as a protected boronic ester intermediate for Suzuki-Miyaura cross-coupling reactions. The tert-butyl carbamate (Boc) group stabilizes the amine functionality during coupling, allowing selective reaction at the boron site. After coupling, the Boc group can be easily removed under mild acidic conditions to liberate the free amine, enabling further functionalization. Commonly employed in the synthesis of pharmaceuticals and bioactive molecules where indane or indoline scaffolds are required. Its stability and compatibility with a wide range of reaction conditions make it valuable in multi-step synthetic routes, especially in drug discovery and development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | $220.85 |
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| 0.250 G | 10-20 days | $432.00 |
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| 1.000 G | 10-20 days | $977.05 |
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| 5.000 G | 10-20 days | $3,419.68 |
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tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl)carbamate
Used primarily in organic synthesis as a protected boronic ester intermediate for Suzuki-Miyaura cross-coupling reactions. The tert-butyl carbamate (Boc) group stabilizes the amine functionality during coupling, allowing selective reaction at the boron site. After coupling, the Boc group can be easily removed under mild acidic conditions to liberate the free amine, enabling further functionalization. Commonly employed in the synthesis of pharmaceuticals and bioactive molecules where indane or indoline scaffolds are required. Its stability and compatibility with a wide range of reaction conditions make it valuable in multi-step synthetic routes, especially in drug discovery and development.
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