5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

95%

  • Product Code: 192702
  CAS:    452105-33-8
Molecular Weight: 300.28 g./mol Molecular Formula: C₁₆H₁₃FN₂O₃
EC Number: MDL Number: MFCD09835575
Melting Point: >295 °C(dec.) Boiling Point: 588.4±50.0 °C(Predicted)
Density: 1.454±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal cell signaling pathways in tumors. Its structure supports binding to specific kinase enzymes, making it valuable in oncology drug research. Also utilized in the preparation of small-molecule inhibitors for use in chronic myeloid leukemia and other solid tumor treatments. Commonly involved in the production of sunitinib analogs due to its ability to enhance selectivity and potency in kinase inhibition.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 G 10-20 days ฿2,530.00
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0.250 G 10-20 days ฿5,910.00
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1.000 G 10-20 days ฿15,620.00
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5.000 G 10-20 days ฿51,810.00
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5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal cell signaling pathways in tumors. Its structure supports binding to specific kinase enzymes, making it valuable in oncology drug research. Also utilized in the preparation of small-molecule inhibitors for use in chronic myeloid leukemia and other solid tumor treatments. Commonly involved in the production of sunitinib analogs due to its ability to enhance selectivity and potency in kinase inhibition.
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