1-(4-Fluorophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
98%
- Product Code: 192711
CAS:
1373918-57-0
| Molecular Weight: | 288.13 g./mol | Molecular Formula: | C₁₅H₁₈BFN₂O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD16987650 | |
| Melting Point: | Boiling Point: | 386.3±22.0 °C(Predicted) | |
| Density: | 1.14±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, facilitating the construction of complex pyrazole derivatives. Commonly employed in the development of fluorinated drug candidates due to enhanced metabolic stability and membrane permeability imparted by the fluorophenyl moiety. Also utilized in materials science for creating novel organic semiconductors and fluorescent probes.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿13,450.00 |
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| 1.000 G | 10-20 days | ฿35,000.00 |
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1-(4-Fluorophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, facilitating the construction of complex pyrazole derivatives. Commonly employed in the development of fluorinated drug candidates due to enhanced metabolic stability and membrane permeability imparted by the fluorophenyl moiety. Also utilized in materials science for creating novel organic semiconductors and fluorescent probes.
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