1-Hydroxy-6-(trifluoromethyl)benzo[c][1,2]oxaborol-3(1H)-one
97%
- Product Code: 192856
CAS:
2828438-87-3
| Molecular Weight: | 215.92 g./mol | Molecular Formula: | C₈H₄BF₃O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 289.7±50.0 °C(Predicted) | |
| Density: | 1.51±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in the synthesis of boron-containing pharmaceuticals, particularly in the development of proteasome inhibitors for cancer therapy. Its unique boron heterocycle structure enhances binding affinity to target enzymes, improving drug efficacy. Also employed in agrochemicals for creating novel fungicides due to its metabolic stability and bioavailability. The trifluoromethyl group contributes to increased lipophilicity and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active compounds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿5,060.00 |
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| 250mg | 10-20 days | ฿8,580.00 |
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1-Hydroxy-6-(trifluoromethyl)benzo[c][1,2]oxaborol-3(1H)-one
Used as a key intermediate in the synthesis of boron-containing pharmaceuticals, particularly in the development of proteasome inhibitors for cancer therapy. Its unique boron heterocycle structure enhances binding affinity to target enzymes, improving drug efficacy. Also employed in agrochemicals for creating novel fungicides due to its metabolic stability and bioavailability. The trifluoromethyl group contributes to increased lipophilicity and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active compounds.
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