1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-4-carbonitrile
98%
- Product Code: 192942
CAS:
1638360-07-2
| Molecular Weight: | 233.07 g./mol | Molecular Formula: | C₁₁H₁₆BN₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22689250 | |
| Melting Point: | Boiling Point: | 385.7±27.0 °C(Predicted) | |
| Density: | 1.11±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, Sealed, Inert Gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in medicinal chemistry for constructing biaryl or heteroaryl frameworks. The nitrile and methyl-substituted pyrazole moieties enhance binding selectivity in bioactive molecules, particularly in kinase inhibitors and anti-inflammatory agents. Commonly employed in late-stage functionalization due to its stability and reactivity under mild conditions.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿14,340.00 |
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| 250mg | 10-20 days | ฿20,480.00 |
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| 1g | 10-20 days | ฿41,440.00 |
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1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-4-carbonitrile
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in medicinal chemistry for constructing biaryl or heteroaryl frameworks. The nitrile and methyl-substituted pyrazole moieties enhance binding selectivity in bioactive molecules, particularly in kinase inhibitors and anti-inflammatory agents. Commonly employed in late-stage functionalization due to its stability and reactivity under mild conditions.
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