2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole hydrate
95%
- Product Code: 192998
CAS:
1288338-69-1
| Molecular Weight: | 371.38 g./mol | Molecular Formula: | C₁₆H₁₆F₃N₃O₂S |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used as a key intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of tenatoprazole and related anti-ulcer agents. Its structure supports the inhibition of gastric acid secretion by targeting the H+/K+-ATPase enzyme in the stomach lining. Due to the presence of trifluoroethoxy and benzimidazole moieties, it exhibits enhanced metabolic stability and binding affinity, making it valuable in developing long-acting PPIs for treating gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The hydrate form improves handling and solubility during pharmaceutical processing.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | ฿1,610.00 |
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| 500.000 | 10-20 days | ฿18,530.00 |
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| 100.000 | 10-20 days | ฿5,290.00 |
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2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole hydrate
Used as a key intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of tenatoprazole and related anti-ulcer agents. Its structure supports the inhibition of gastric acid secretion by targeting the H+/K+-ATPase enzyme in the stomach lining. Due to the presence of trifluoroethoxy and benzimidazole moieties, it exhibits enhanced metabolic stability and binding affinity, making it valuable in developing long-acting PPIs for treating gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The hydrate form improves handling and solubility during pharmaceutical processing.
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