3-(5-Methyl-1H-tetrazol-1-yl)benzoic acid
98%
- Product Code: 193068
CAS:
799262-37-6
| Molecular Weight: | 204.19 g./mol | Molecular Formula: | C₉H₈N₄O₂ |
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| EC Number: | MDL Number: | MFCD04113966 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature |
Product Description:
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving receptor binding affinity. It is a key intermediate in pharmaceuticals like candesartan and related compounds, contributing to their effectiveness in managing high blood pressure. Its structure allows for better oral bioavailability and longer duration of action in vivo.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | €109.15 |
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3-(5-Methyl-1H-tetrazol-1-yl)benzoic acid
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving receptor binding affinity. It is a key intermediate in pharmaceuticals like candesartan and related compounds, contributing to their effectiveness in managing high blood pressure. Its structure allows for better oral bioavailability and longer duration of action in vivo.
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