5-Phenyl-1-trityl-1H-tetrazole
98%
- Product Code: 193182
CAS:
154750-11-5
| Molecular Weight: | 388.46 g./mol | Molecular Formula: | C₂₆H₂₀N₄ |
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. It serves as a protected tetrazole building block, enabling selective reactions at other functional sites during multi-step pharmaceutical syntheses. Its trityl (triphenylmethyl) group provides stability and prevents unwanted side reactions, making it valuable in solid-phase and solution-phase peptide and heterocycle chemistry. Also employed in the development of novel bioactive molecules where the tetrazole ring acts as a bioisostere for carboxylic acid groups.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5g | 10-20 days | ฿50,900.00 |
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5-Phenyl-1-trityl-1H-tetrazole
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. It serves as a protected tetrazole building block, enabling selective reactions at other functional sites during multi-step pharmaceutical syntheses. Its trityl (triphenylmethyl) group provides stability and prevents unwanted side reactions, making it valuable in solid-phase and solution-phase peptide and heterocycle chemistry. Also employed in the development of novel bioactive molecules where the tetrazole ring acts as a bioisostere for carboxylic acid groups.
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