1-(methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
98%
- Product Code: 194278
CAS:
944994-03-0
| Molecular Weight: | 272.13 g./mol | Molecular Formula: | C₁₀H₁₇BN₂O₄S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18383275 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex nitrogen-containing heterocycles found in bioactive molecules. Due to the methylsulfonyl group's electron-withdrawing properties, it enhances the stability and reactivity profile in such transformations. It is especially useful in medicinal chemistry for rapid diversification of pyrazole-based scaffolds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿1,240.00 |
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| 250mg | 10-20 days | ฿2,050.00 |
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| 1g | 10-20 days | ฿5,460.00 |
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| 5g | 10-20 days | ฿20,680.00 |
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1-(methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex nitrogen-containing heterocycles found in bioactive molecules. Due to the methylsulfonyl group's electron-withdrawing properties, it enhances the stability and reactivity profile in such transformations. It is especially useful in medicinal chemistry for rapid diversification of pyrazole-based scaffolds.
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